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Great Point Partners LLC 13F filings

Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin

Holdings as of 2022-09-30

Filed on 2022-11-14 under CIK 1281446

Company
Investment Type
Change
Value (x$1000)
increase or decrease
XENON PHARMACEUTICALS INC COM
850,000 sh
-254,334 sh
-23%
$30,685
-$2,909
Jazz Pharmaceuticals Plc
215,000 sh
25,000 sh
13%
$28,657
-$985
Point Biopharma Global Inc. COM
3,560,984 sh
1,140,483 sh
47%
$27,526
$11,042
ALPINE IMMUNE SCIENCES INC COM
3,448,521 sh
2,909,702 sh
540%
$24,829
$20,244
Travere Therapeutics Inc
966,108 sh
-5,125 sh
-1%
$23,805
$272
Heron Therapeutics Inc
5,645,161 sh
5,645,161 sh
NEW
$23,484
$23,484
KALVISTA PHARMACEUTICALS INC COM
1,551,719 sh
21,719 sh
1%
$22,515
$7,460
Pliant Therapeutics Inc. COM
1,041,737 sh
684,474 sh
192%
$21,762
$18,900
RELMADA THERAPEUTICS INC COM
510,000 sh
-190,000 sh
-27%
$18,880
$5,587
ACLARIS THERAPEUTICS INC COM
1,019,282 sh
-63,718 sh
-6%
$16,043
$924
Vaxcyte, Inc. COM
600,000 sh
-385,153 sh
-39%
$14,400
-$7,037
GALAPAGOS NV SPON ADR
306,411 sh
-53,589 sh
-15%
$13,065
-$7,023
Acumen Pharmaceuticals Inc. COM
1,200,000 sh
-315,000 sh
-21%
$12,036
$4,915
Alkermes
507,500 sh
145,864 sh
40%
$11,332
$559
Seagen Inc.
76,500 sh
76,500 sh
NEW
$10,467
$10,467
Bridgebio Pharma Inc. COM
1,050,000 sh
1,050,000 sh
NEW
$10,437
$10,437
CINCOR PHARMA INC COM
301,324 sh
-367,876 sh
-55%
$9,889
-$2,719
VENTYX BIOSCIENCES INC COM
269,967 sh
-119,256 sh
-31%
$9,425
$4,665
TRICIDA INC COM
870,000 sh
-294,763 sh
-25%
$9,118
-$2,157
RAPT Therapeutics Inc.
315,000 sh
315,000 sh
NEW
$7,579
$7,579
UroGen Pharma Ltd. COM
873,424 sh
 
$7,267
REPLIMUNE GROUP INC COM
390,000 sh
390,000 sh
NEW
$6,735
$6,735
MADRIGAL PHARMACEUTICALS INC COM
95,500 sh
95,500 sh
NEW
$6,207
$6,207
MILESTONE PHARMACEUTICALS IN COM
674,656 sh
674,656 sh
NEW
$6,200
$6,200
89BIO INC COM
955,000 sh
-445,000 sh
-32%
$5,529
$1,021
Generation Bio Co. COM
825,077 sh
825,077 sh
NEW
$4,381
$4,381
NGM Biopharmaceuticals Inc.
316,256 sh
316,256 sh
NEW
$4,137
$4,137
MOONLAKE IMMUNOT COMMON STOCK
492,000 sh
60,000 sh
14%
$3,818
$1,550
IMMUNOCORE HOLDINGS PLC-ADR (IMCR US) ADS
78,527 sh
78,527 sh
NEW
$3,686
$3,686
LARIMAR THERAPEUTICS INC COMMON STOCK
1,135,000 sh
1,135,000 sh
NEW
$3,632
$3,632
Precision BioSciences Inc.
2,710,805 sh
-3,044,591 sh
-53%
$3,524
-$5,685
CYMABAY THERAPEUTICS INC COM
799,439 sh
799,439 sh
NEW
$2,798
$2,798
Pieris Pharmaceuticals Inc
1,965,449 sh
-547,051 sh
-22%
$2,260
-$2,438
Intercept Pharmaceuticals Inc
105,000 sh
105,000 sh
NEW
$1,465
$1,465
GRACELL BIOTECHNOLOGIES INC ADR
449,049 sh
449,049 sh
NEW
$1,446
$1,446
Magenta Therapeutics Inc COM
1,019,091 sh
-150,909 sh
-13%
$1,437
$33
Nektar Therapeutics
447,820 sh
-2,702,180 sh
-86%
$1,433
-$10,537
Day One Biopharmaceuticals Inc. COM
70,621 sh
70,621 sh
NEW
$1,415
$1,415
AEGLEA BIOTHERAPEUTICS INC COM
2,500,000 sh
 
$1,315
SILENCE THERAPEUTICS PLC ADS
68,915 sh
-332,534 sh
-83%
$692
-$4,065
CYTOKINETICS INC COM NEW
0 sh
-610,000 sh
-100%
$0
-$23,967
Alnylam Pharmaceuticals Inc

Put options for 0 sh
-150,000 sh
-100%
$0
-$21,878
Sarepta Therapeutics Inc
0 sh
-193,900 sh
-100%
$0
-$14,535
KINIKSA PHARMACEUTICALS LTD COM CL A
0 sh
-1,204,028 sh
-100%
$0
-$11,667
AnaptysBio Inc.
0 sh
-453,118 sh
-100%
$0
-$9,198
Neurocrine Biosciences Inc
0 sh
-75,000 sh
-100%
$0
-$7,311
Avidity Biosciences, Inc.
0 sh
-500,000 sh
-100%
$0
-$7,265
KARUNA THERAPEUTICS INC COM

Put options for 0 sh
-54,900 sh
-100%
$0
-$6,945
Chinook Therapeutics
0 sh
-336,731 sh
-100%
$0
-$5,889