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Great Point Partners LLC 13F filings

Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin

Holdings as of 2020-09-30

Filed on 2020-11-16 under CIK 1281446

Company name, stock class and CUSIPValue (x$1000) SharesOther manager(s)
IOVANCE BIOTHERAPEUTICS INC
COM 462260100
$127,618$25,3673,876,600 sh151,624 sh
4%
JAY JEFFREY R
Yehudai Ortav
SAGE THERAPEUTICS INC
COM 78667J108
$120,204$32,7881,966,688 sh-135,680 sh
-6%
JAY JEFFREY R
Yehudai Ortav
ACADIA PHARMACEUTICALS INC
COM 004225108
$79,264-$8,2241,921,563 sh116,570 sh
6%
JAY JEFFREY R
Yehudai Ortav
ARENA PHARMACEUTICALS INC
COM NEW 040047607
$74,558-$7,428996,898 sh-305,501 sh
-23%
JAY JEFFREY R
Yehudai Ortav
ZYMEWORKS INC
COM 98985W102
$73,033-$19,8361,567,900 sh-1,006,788 sh
-39%
JAY JEFFREY R
Yehudai Ortav
UNITED THERAPEUTICS CORP DEL
COM 91307C102
$64,718-$10,302640,773 sh20,773 sh
3%
JAY JEFFREY R
Yehudai Ortav
CONSTELLATION PHARMCETICLS I
COM 210373106
$57,983-$46,5912,861,924 sh-618,076 sh
-18%
JAY JEFFREY R
Yehudai Ortav
CYTOKINETICS INC
COM NEW 23282W605
$55,197$19,3562,549,525 sh1,028,890 sh
68%
JAY JEFFREY R
Yehudai Ortav
GW PHARMACEUTICALS PLC
ADS 36197T103
$50,645-$4,579520,232 sh70,232 sh
16%
JAY JEFFREY R
Yehudai Ortav
TG THERAPEUTICS INC
COM 88322Q108
$42,816-$21,8731,600,000 sh-1,720,808 sh
-52%
JAY JEFFREY R
Yehudai Ortav
MACROGENICS INC
COM 556099109
$38,042-$3,8381,510,215 sh10,215 sh
1%
JAY JEFFREY R
Yehudai Ortav
AURINIA PHARMACEUTICALS INC
COM 05156V102
$36,609$36,6092,485,327 sh2,485,327 sh
NEW
JAY JEFFREY R
Yehudai Ortav
GLOBAL BLOOD THERAPEUTICS INC
COM 37890U108
$36,154$1,925655,676 sh113,476 sh
21%
JAY JEFFREY R
Yehudai Ortav
BIOHAVEN PHARMACTL HLDG CO L
COM G11196105
$28,279-$33,199435,000 sh-405,900 sh
-48%
JAY JEFFREY R
Yehudai Ortav
Vericel Corp
COM 92346J108
$27,439$5,1871,480,787 sh-129,367 sh
-8%
JAY JEFFREY R
Yehudai Ortav
GLAUKOS CORP
COM 377322102
$22,091$2,881446,097 sh-53,903 sh
-11%
JAY JEFFREY R
Yehudai Ortav
GERON CORP
COM 374163103
$16,853-$16,7159,685,528 sh-5,712,551 sh
-37%
JAY JEFFREY R
Yehudai Ortav
PROTHENA CORP PLC
SHS G72800108
$15,469-$6,3181,548,479 sh-534,362 sh
-26%
JAY JEFFREY R
Yehudai Ortav
SANGAMO THERAPEUTICS INC
COM 800677106
$15,023$8671,589,724 sh9,833 sh
1%
JAY JEFFREY R
Yehudai Ortav
CHEMOCENTRYX INC
COM 16383L106
$13,877$13,877253,230 sh253,230 sh
NEW
JAY JEFFREY R
Yehudai Ortav
TRANSLATE BIO INC
COM 89374L104
$12,839$12,839943,339 sh943,339 sh
NEW
JAY JEFFREY R
Yehudai Ortav
ALLOGENE THERAPEUTICS INC
COM 019770106
$12,400$12,400328,817 sh328,817 sh
NEW
JAY JEFFREY R
Yehudai Ortav
INTERSECT ENT INC
COM 46071F103
$12,199$12,199747,926 sh747,926 sh
NEW
JAY JEFFREY R
Yehudai Ortav
INVENTIVA SA
ADS 46124U107
$11,813$11,813999,422 sh999,422 sh
NEW
JAY JEFFREY R
Yehudai Ortav
PUMA BIOTECHNOLOGY INC
COM 74587V107
$11,120$10,1551,102,073 sh1,009,571 sh
1091%
JAY JEFFREY R
Yehudai Ortav
CALITHERA BIOSCIENCES INC
COM 13089P101
$10,069-$1,8732,918,581 sh656,881 sh
29%
JAY JEFFREY R
Yehudai Ortav
KADMON HLDGS INC
COM 48283N106
$9,800$6,3412,500,000 sh1,824,321 sh
270%
JAY JEFFREY R
Yehudai Ortav
VIEWRAY INC
COM 92672L107
$9,295$3,0822,655,763 sh-118,048 sh
-4%
JAY JEFFREY R
Yehudai Ortav
LANTHEUS HLDGS INC
COM 516544103
$7,535$7,535594,750 sh594,750 sh
NEW
JAY JEFFREY R
Yehudai Ortav
LIQUIDIA TECHNOLOGIES INC
COM 53635D202
$5,853-$4,9071,189,607 sh-88,348 sh
-7%
JAY JEFFREY R
Yehudai Ortav
CYTOKINETICS INC
COM NEW 23282W605
$5,477$5,477Put options for
253,000 sh
253,000 sh
NEW
JAY JEFFREY R
Yehudai Ortav
ABEONA THERAPEUTICS INC
COM 00289Y107
$3,971-$17,0553,892,921 sh-3,320,091 sh
-46%
JAY JEFFREY R
Yehudai Ortav
MILLENDO THERAPEUTICS INC
COM 60040X103
$1,920-$6511,177,900 sh-282,797 sh
-19%
JAY JEFFREY R
Yehudai Ortav
OYSTER POINT PHARMA INC
COM 69242L106
$1,480-$4,71970,121 sh-144,510 sh
-67%
JAY JEFFREY R
Yehudai Ortav
AKEBIA THERAPEUTICS INC
COM 00972D105
$0-$47,6670 sh-3,510,073 sh
-100%
JAY JEFFREY R
Yehudai Ortav
NEXTCURE INC
COM 65343E108
$0-$21,4330 sh-999,666 sh
-100%
JAY JEFFREY R
Yehudai Ortav
MOLECULAR TEMPLATES INC
COM 608550109
$0-$18,5530 sh-1,345,397 sh
-100%
JAY JEFFREY R
Yehudai Ortav
PTC THERAPEUTICS INC
COM 69366J200
$0-$16,7440 sh-330,000 sh
-100%
JAY JEFFREY R
Yehudai Ortav
AXONICS MODULATION TECH INC
COM 05465P101
$0-$16,1330 sh-459,503 sh
-100%
JAY JEFFREY R
Yehudai Ortav
Cytomx Therapeutics Inc
COM 23284F105
$0-$12,0670 sh-1,448,604 sh
-100%
JAY JEFFREY R
Yehudai Ortav
ARVINAS INC
COM 04335A105
$0-$6,825Call options for
0 sh
-203,500 sh
-100%
JAY JEFFREY R
Yehudai Ortav
Denali Therapeutics
COM 24823R105
$0-$6,7700 sh-280,000 sh
-100%
JAY JEFFREY R
Yehudai Ortav
Acceleron Pharma Inc
COM 00434H108
$0-$5,5310 sh-58,056 sh
-100%
JAY JEFFREY R
Yehudai Ortav
NEOLEUKIN THERAPEUTICS INC
COM 64049K104
$0-$2330 sh-14,065 sh
-100%
JAY JEFFREY R
Yehudai Ortav