Manager(s): Dr. Jeffrey R. Jay, M.D. and Mr. David E. Kroin
Filed on 2020-08-14 under CIK 1281446
| Company name, stock class and CUSIP | Value (x$1000) | Shares | Other manager(s) | ||
|---|---|---|---|---|---|
| CONSTELLATION PHARMCETICLS I COM 210373106 |
$104,574 | $42,421 | 3,480,000 sh | 1,502,498 sh 76% | JAY JEFFREY R KROIN DAVID |
| IOVANCE BIOTHERAPEUTICS INC COM 462260100 |
$102,251 | $30,778 | 3,724,976 sh | 1,337,370 sh 56% | JAY JEFFREY R KROIN DAVID |
| ZYMEWORKS INC COM 98985W102 |
$92,869 | $10,412 | 2,574,688 sh | 250,000 sh 11% | JAY JEFFREY R KROIN DAVID |
| ACADIA PHARMACEUTICALS INC COM 004225108 |
$87,488 | $3,168 | 1,804,993 sh | -190,754 sh
-10% | JAY JEFFREY R KROIN DAVID |
| SAGE THERAPEUTICS INC COM 78667J108 |
$87,416 | $35,017 | 2,102,368 sh | 277,889 sh 15% | JAY JEFFREY R KROIN DAVID |
| ARENA PHARMACEUTICALS INC COM NEW 040047607 |
$81,986 | $65,711 | 1,302,399 sh | 914,900 sh 236% | JAY JEFFREY R KROIN DAVID |
| UNITED THERAPEUTICS CORP DEL COM 91307C102 |
$75,020 | $22,273 | 620,000 sh | 63,748 sh 11% | JAY JEFFREY R KROIN DAVID |
| TG THERAPEUTICS INC COM 88322Q108 |
$64,689 | $54,849 | 3,320,808 sh | 2,320,808 sh 232% | JAY JEFFREY R KROIN DAVID |
| BIOHAVEN PHARMACTL HLDG CO L COM G11196105 |
$61,478 | $27,448 | 840,900 sh | -159,100 sh
-16% | JAY JEFFREY R KROIN DAVID |
| GW PHARMACEUTICALS PLC ADS 36197T103 |
$55,224 | 450,000 sh | JAY JEFFREY R KROIN DAVID | ||
| AKEBIA THERAPEUTICS INC COM 00972D105 |
$47,667 | $47,667 | 3,510,073 sh | 3,510,073 sh NEW | JAY JEFFREY R KROIN DAVID |
| MACROGENICS INC COM 556099109 |
$41,880 | $41,880 | 1,500,000 sh | 1,500,000 sh NEW | JAY JEFFREY R KROIN DAVID |
| CYTOKINETICS INC COM NEW 23282W605 |
$35,841 | $28,011 | 1,520,635 sh | 856,538 sh 129% | JAY JEFFREY R KROIN DAVID |
| GLOBAL BLOOD THERAPEUTICS INC COM 37890U108 |
$34,229 | $34,229 | 542,200 sh | 542,200 sh NEW | JAY JEFFREY R KROIN DAVID |
| GERON CORP COM 374163103 |
$33,568 | $33,568 | 15,398,079 sh | 15,398,079 sh NEW | JAY JEFFREY R KROIN DAVID |
| Vericel Corp COM 92346J108 |
$22,252 | $22,252 | 1,610,154 sh | 1,610,154 sh NEW | JAY JEFFREY R KROIN DAVID |
| PROTHENA CORP PLC SHS G72800108 |
$21,787 | 2,082,841 sh | JAY JEFFREY R KROIN DAVID | ||
| NEXTCURE INC COM 65343E108 |
$21,433 | -$27,238 | 999,666 sh | -313,290 sh
-24% | JAY JEFFREY R KROIN DAVID |
| ABEONA THERAPEUTICS INC COM 00289Y107 |
$21,026 | 7,213,012 sh | JAY JEFFREY R KROIN DAVID | ||
| GLAUKOS CORP COM 377322102 |
$19,210 | $19,210 | 500,000 sh | 500,000 sh NEW | JAY JEFFREY R KROIN DAVID |
| MOLECULAR TEMPLATES INC COM 608550109 |
$18,553 | $7,589 | 1,345,397 sh | 520,397 sh 63% | JAY JEFFREY R KROIN DAVID |
| PTC THERAPEUTICS INC COM 69366J200 |
$16,744 | -$61,921 | 330,000 sh | -1,433,387 sh
-81% | JAY JEFFREY R KROIN DAVID |
| AXONICS MODULATION TECH INC COM 05465P101 |
$16,133 | $2,337 | 459,503 sh | -83,426 sh
-15% | JAY JEFFREY R KROIN DAVID |
| SANGAMO THERAPEUTICS INC COM 800677106 |
$14,156 | $10,121 | 1,579,891 sh | 946,386 sh 149% | JAY JEFFREY R KROIN DAVID |
| Cytomx Therapeutics Inc COM 23284F105 |
$12,067 | $10,995 | 1,448,604 sh | 1,308,886 sh 937% | JAY JEFFREY R KROIN DAVID |
| CALITHERA BIOSCIENCES INC COM 13089P101 |
$11,942 | $11,942 | 2,261,700 sh | 2,261,700 sh NEW | JAY JEFFREY R KROIN DAVID |
| LIQUIDIA TECHNOLOGIES INC COM 53635D202 |
$10,760 | 1,277,955 sh | JAY JEFFREY R KROIN DAVID | ||
| ARVINAS INC COM 04335A105 |
$6,825 | $2,654 | Call options for 203,500 sh | 100,000 sh 97% | JAY JEFFREY R KROIN DAVID |
| Denali Therapeutics COM 24823R105 |
$6,770 | $6,770 | 280,000 sh | 280,000 sh NEW | JAY JEFFREY R KROIN DAVID |
| VIEWRAY INC COM 92672L107 |
$6,213 | 2,773,811 sh | JAY JEFFREY R KROIN DAVID | ||
| OYSTER POINT PHARMA INC COM 69242L106 |
$6,199 | $6,199 | 214,631 sh | 214,631 sh NEW | JAY JEFFREY R KROIN DAVID |
| Acceleron Pharma Inc COM 00434H108 |
$5,531 | -$42,606 | 58,056 sh | -477,571 sh
-89% | JAY JEFFREY R KROIN DAVID |
| KADMON HLDGS INC COM 48283N106 |
$3,459 | $3,459 | 675,679 sh | 675,679 sh NEW | JAY JEFFREY R KROIN DAVID |
| MILLENDO THERAPEUTICS INC COM 60040X103 |
$2,571 | -$6,562 | 1,460,697 sh | -269,062 sh
-16% | JAY JEFFREY R KROIN DAVID |
| PUMA BIOTECHNOLOGY INC COM 74587V107 |
$965 | $965 | 92,502 sh | 92,502 sh NEW | JAY JEFFREY R KROIN DAVID |
| NEOLEUKIN THERAPEUTICS INC COM 64049K104 |
$233 | -$226 | 14,065 sh | -26,282 sh
-65% | JAY JEFFREY R KROIN DAVID |
| ABIOMED INC COM 003654100 |
$0 | -$31,375 | 0 sh | -216,144 sh
-100% | JAY JEFFREY R KROIN DAVID |
| MOMENTA PHARMACEUTICALS INC COM 60877T100 |
$0 | -$26,640 | 0 sh | -979,400 sh
-100% | JAY JEFFREY R KROIN DAVID |
| MYOKARDIA INC COM 62857M105 |
$0 | -$23,440 | Call options for 0 sh | -500,000 sh
-100% | JAY JEFFREY R KROIN DAVID |
| CHEMOCENTRYX INC COM 16383L106 |
$0 | -$14,359 | 0 sh | -357,379 sh
-100% | JAY JEFFREY R KROIN DAVID |
| AXSOME THERAPEUTICS INC COM 05464T104 |
$0 | -$5,889 | 0 sh | -100,100 sh
-100% | JAY JEFFREY R KROIN DAVID |
| MENLO THERAPEUTICS INC COM 586858102 |
$0 | -$4,427 | 0 sh | -1,652,013 sh
-100% | JAY JEFFREY R KROIN DAVID |
| KURA ONCOLOGY INC COM 50127T109 |
$0 | -$1,788 | 0 sh | -179,700 sh
-100% | JAY JEFFREY R KROIN DAVID |