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Great Point Partners 13F filings

Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin

Holdings as of 2023-09-30

Filed on 2023-11-14 under CIK 1281446

Company
Investment Type
Change
Value (x$1000)
increase or decrease
UroGen Pharma Ltd. COM
2,620,545 sh
2,620,545 sh
NEW
$36,714
$36,714
ALPINE IMMUNE SCIENCES INC COM
3,078,633 sh
-285,055 sh
-8%
$35,250
$671
Pliant Therapeutics Inc. COM
1,755,184 sh
205,000 sh
13%
$30,435
$2,346
Vaxcyte, Inc. COM
531,211 sh
-58,000 sh
-10%
$27,081
-$2,344
Ultragenyx Pharmaceutical Inc
727,426 sh
50,000 sh
7%
$25,933
-$5,317
Alkermes
875,044 sh
463,591 sh
113%
$24,510
$11,632
RAPT Therapeutics Inc.
1,458,070 sh
-7,081 sh
0%
$24,233
-$3,165
ZURA BIO LTD CLASS A ORD SHS
3,295,000 sh
 
$21,747
Sarepta Therapeutics Inc
165,200 sh
41,600 sh
34%
$20,026
$5,871
EVOLUS INC COM
2,186,934 sh
-247,114 sh
-10%
$19,989
$2,293
Point Biopharma Global Inc. COM
2,909,960 sh
-90,040 sh
-3%
$19,409
-$7,771
CYTOKINETICS INC COM NEW
600,000 sh
 
$17,676
XENON PHARMACEUTICALS INC COM
500,001 sh
497,301 sh
18419%
$17,080
$16,976
AnaptysBio Inc.
894,333 sh
 
$16,062
IMMUNOCORE HOLDINGS PLC-ADR (IMCR US) ADS
290,917 sh
-6,165 sh
-2%
$15,099
-$2,714
Aerovate Therapeutics Inc. COM
1,091,233 sh
159,075 sh
17%
$14,808
-$1,179
INTRA CELLULAR THERAPIES INC COM
225,000 sh
225,000 sh
NEW
$11,720
$11,720
ACLARIS THERAPEUTICS INC COM
1,691,768 sh
1,436,768 sh
563%
$11,589
$8,945
Sarepta Therapeutics Inc

Put options for 95,000 sh
95,000 sh
NEW
$11,516
$11,516
PTC Therapeutics Inc.
500,000 sh
500,000 sh
NEW
$11,205
$11,205
REPLIMUNE GROUP INC COM
638,495 sh
638,495 sh
NEW
$10,925
$10,925
Optinose Inc
8,839,939 sh
 
$10,873
Amicus Therapeutics Inc
857,000 sh
155,608 sh
22%
$10,421
$1,612
ARCELLX INC
287,500 sh
250,000 sh
667%
$10,316
$9,130
KARUNA THERAPEUTICS INC COM
60,500 sh
60,500 sh
NEW
$10,230
$10,230
AKERO THERAPEUTICS INC COM
198,500 sh
198,500 sh
NEW
$10,040
$10,040
INSMED INC COM PAR $.01
394,872 sh
394,872 sh
NEW
$9,971
$9,971
Reneo Pharmaceuticals Inc. COM
1,167,061 sh
83,744 sh
8%
$8,887
$1,780
APOGEE THERAPEUTICS INC COM
400,000 sh
400,000 sh
NEW
$8,520
$8,520
GOSSAMER BIO INC COM
6,230,272 sh
6,230,272 sh
NEW
$5,189
$5,189
IGM BIOSCIENCES INC COM
615,317 sh
115,317 sh
23%
$5,138
$523
Heron Therapeutics Inc
4,737,368 sh
 
$4,879
ACLARIS THERAPEUTICS INC COM

Call options for 700,000 sh
700,000 sh
NEW
$4,795
$4,795
Cerevel Therapeutics Holdings Inc. COM
215,000 sh
215,000 sh
NEW
$4,693
$4,693
Acumen Pharmaceuticals Inc. COM
1,074,101 sh
22,834 sh
2%
$4,458
-$599
Generation Bio Co. COM
1,022,537 sh
 
$3,875
MIRATI THERAPEUTICS INC COM
86,302 sh
86,302 sh
NEW
$3,759
$3,759
Terns Pharmaceuticals Inc. COM
645,899 sh
645,899 sh
NEW
$3,249
$3,249
Talaris Therapeutics Inc. COM
1,000,000 sh
333,967 sh
50%
$2,810
$785
GRACELL BIOTECHNOLOGIES INC ADR
579,667 sh
-1,688,390 sh
-74%
$1,669
-$6,972
undefined
450,403 sh
-134,055 sh
-23%
$1,135
-$1,928
AMBRX BIOPHARMA INC SPONSORED ADS

Call options for 97,700 sh
97,700 sh
NEW
$1,124
$1,124
AMYLYX PHARMACEUTICALS INC
0 sh
-968,795 sh
-100%
$0
-$20,897
RHYTHM PHARMACEUTICALS INC COM
0 sh
-772,000 sh
-100%
$0
-$12,730
VIKING THERAPEUTICS INC COM
0 sh
-598,550 sh
-100%
$0
-$9,702
MINERALYS THERAPEUTICS INC COM
0 sh
-546,059 sh
-100%
$0
-$9,310
APELLIS PHARMACEUTICALS INC COM

Put options for 0 sh
-94,700 sh
-100%
$0
-$8,627
Intercept Pharmaceuticals Inc COM
0 sh
-601,322 sh
-100%
$0
-$6,651
4D Molecular Therapeutics Inc.
0 sh
-350,000 sh
-100%
$0
-$6,325
Seres Therapeutics Inc
0 sh
-938,067 sh
-100%
$0
-$4,493
Precision BioSciences Inc.
0 sh
-7,469,736 sh
-100%
$0
-$3,929
Travere Therapeutics Inc
0 sh
-60,000 sh
-100%
$0
-$922
Mersana Therapeutics Inc

Call options for 0 sh
-70,000 sh
-100%
$0
-$230
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