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Great Point Partners 13F filings

Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin

Holdings as of 2023-12-31

Filed on 2024-02-14 under CIK 1281446

Company
Investment Type
Change
Value (x$1000)
increase or decrease
ALPINE IMMUNE SCIENCES INC COM
3,703,433 sh
624,800 sh
20%
$70,587
$35,337
CYTOKINETICS INC COM NEW
500,000 sh
-100,000 sh
-17%
$41,745
$24,069
UroGen Pharma Ltd. COM
2,620,545 sh
 
$39,308
Pliant Therapeutics Inc. COM
1,823,184 sh
68,000 sh
4%
$33,018
$2,583
Ultragenyx Pharmaceutical Inc
648,000 sh
-79,426 sh
-11%
$30,987
$5,054
XENON PHARMACEUTICALS INC COM
600,000 sh
99,999 sh
20%
$27,636
$10,556
RAPT Therapeutics Inc.
1,099,753 sh
-358,317 sh
-25%
$27,329
$3,096
Alkermes
875,044 sh
 
$24,274
Aerovate Therapeutics Inc. COM
1,037,690 sh
-53,543 sh
-5%
$23,483
$8,675
Vaxcyte, Inc. COM
360,000 sh
-171,211 sh
-32%
$22,608
-$4,473
EVOLUS INC COM
2,000,000 sh
-186,934 sh
-9%
$21,060
$1,071
AnaptysBio Inc.
976,981 sh
82,648 sh
9%
$20,927
$4,865
IMMUNOCORE HOLDINGS PLC-ADR (IMCR US) ADS
293,000 sh
2,083 sh
1%
$20,018
$4,919
NEUROGENE INC COM
994,229 sh
994,229 sh
NEW
$19,268
$19,268
Amicus Therapeutics Inc
1,280,500 sh
423,500 sh
49%
$18,170
$7,749
TOURMALINE BIO INC Common Stock
672,885 sh
672,885 sh
NEW
$17,616
$17,616
Abivax SA F Sponsored ADR Stock
1,550,000 sh
1,550,000 sh
NEW
$16,585
$16,585
ZURA BIO LTD CLASS A ORD SHS
3,295,000 sh
 
$15,388
Optinose Inc
8,839,939 sh
 
$11,404
APOGEE THERAPEUTICS INC COM
400,000 sh
 
$11,176
Arvinas Inc COM
234,082 sh
234,082 sh
NEW
$9,635
$9,635
KARUNA THERAPEUTICS INC COM
30,250 sh
-30,250 sh
-50%
$9,574
-$656
VISTAGEN THERAPEUTICS ORD COM
1,858,735 sh
1,858,735 sh
NEW
$9,554
$9,554
Terns Pharmaceuticals Inc. COM
1,309,975 sh
664,076 sh
103%
$8,502
$5,253
INTRA CELLULAR THERAPIES INC COM
110,607 sh
-114,393 sh
-51%
$7,922
-$3,798
Sarepta Therapeutics Inc
80,000 sh
-15,000 sh
-16%
$7,714
-$3,802
INSMED INC COM PAR $.01
225,912 sh
-168,960 sh
-43%
$7,001
-$2,970
PUMA BIOTECHNOLOGY INC COM
1,093,273 sh
1,093,273 sh
NEW
$4,734
$4,734
Ocular Therapeutix Inc
700,000 sh
700,000 sh
NEW
$3,122
$3,122
AEGLEA BIOTHERAPEUTICS INC cs
125,000 sh
125,000 sh
NEW
$2,690
$2,690
ARCELLX INC
48,264 sh
-239,236 sh
-83%
$2,679
-$7,637
MERUS N V COM
20,000 sh
20,000 sh
NEW
$550
$550
AXSOME THERAPEUTICS INC COM
4,963 sh
4,963 sh
NEW
$395
$395
Mural Oncology PLC Common / Ordinary Stock
11,509 sh
11,509 sh
NEW
$68
$68
Point Biopharma Global Inc. COM
0 sh
-2,909,960 sh
-100%
$0
-$19,409
PTC Therapeutics Inc.
0 sh
-500,000 sh
-100%
$0
-$11,205
REPLIMUNE GROUP INC COM
0 sh
-638,495 sh
-100%
$0
-$10,925
AKERO THERAPEUTICS INC COM
0 sh
-198,500 sh
-100%
$0
-$10,040
Reneo Pharmaceuticals Inc. COM
0 sh
-1,167,061 sh
-100%
$0
-$8,887
GOSSAMER BIO INC COM
0 sh
-6,230,272 sh
-100%
$0
-$5,189
IGM BIOSCIENCES INC COM
0 sh
-615,317 sh
-100%
$0
-$5,138
Heron Therapeutics Inc
0 sh
-4,737,368 sh
-100%
$0
-$4,879
ACLARIS THERAPEUTICS INC COM

Call options for 0 sh
-700,000 sh
-100%
$0
-$4,795
Cerevel Therapeutics Holdings Inc. COM
0 sh
-215,000 sh
-100%
$0
-$4,693
Acumen Pharmaceuticals Inc. COM
0 sh
-1,074,101 sh
-100%
$0
-$4,458
Generation Bio Co. COM
0 sh
-1,022,537 sh
-100%
$0
-$3,875
MIRATI THERAPEUTICS INC COM
0 sh
-86,302 sh
-100%
$0
-$3,759
Talaris Therapeutics Inc. COM
0 sh
-1,000,000 sh
-100%
$0
-$2,810
GRACELL BIOTECHNOLOGIES INC ADR
0 sh
-579,667 sh
-100%
$0
-$1,669
Solid Biosciences Inc
0 sh
-450,403 sh
-100%
$0
-$1,135
AMBRX BIOPHARMA INC SPONSORED ADS

Call options for 0 sh
-97,700 sh
-100%
$0
-$1,124