Great Point Partners 13F filings
Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin
Holdings as of 2025-09-30
Filed on 2025-11-14 under CIK 1281446
Company
Investment Type
Change
Value (x$1000)
increase or decrease
AMYLYX PHARMACEUTICALS INC COM
1,700,000 sh
-300,000 sh
-15%
-15%
$23,103
$10,283
Rezolute Inc. COM NEW
2,451,809 sh
-581,653 sh
-19%
-19%
$23,047
$9,518
NEKTAR THERAPEUTICS COM NEW
300,000 sh
300,000 sh
NEW
NEW
$17,070
$17,070
ZURA BIO LTD CLASS A ORD SHS
3,815,930 sh
645,736 sh
20%
20%
$16,523
$13,194
SOLENO THERAPEUTICS INC COM
225,000 sh
225,000 sh
NEW
NEW
$15,210
$15,210
ASCENDIS PHARMA A S SPONSORED ADR
75,000 sh
75,000 sh
NEW
NEW
$14,911
$14,911
Abivax SA F Sponsored ADR Stock
150,000 sh
-1,141,617 sh
-88%
-88%
$12,735
$2,854
APOGEE THERAPEUTICS INC COM
304,000 sh
304,000 sh
NEW
NEW
$12,078
$12,078
DIANTHUS THERAPEUTICS INC COM
265,803 sh
265,803 sh
NEW
NEW
$10,459
$10,459
CYTOKINETICS INC COM NEW
150,000 sh
$8,244
IMMUNOVANT INC COM
500,000 sh
237,824 sh
91%
91%
$8,060
$3,865
XENON PHARMACEUTICALS INC COM
200,000 sh
$8,030
NEUROGENE INC COM
446,814 sh
-39,045 sh
-8%
-8%
$7,743
$479
EUPRAXIA PHARMACEUTICALS INC COM
1,200,000 sh
1,200,000 sh
NEW
NEW
$7,080
$7,080
UPSTREAM BIO INC COM
300,000 sh
$5,643
JADE BIOSCIENCES INC COM NEW
632,599 sh
134,545 sh
27%
27%
$5,459
$483
AKERO THERAPEUTICS INC COM
103,848 sh
$4,931
Taysha Gene Therapies Inc. COM
1,500,000 sh
$4,905
CONTEXT THERAPEUTICS INC COM COM
4,683,711 sh
$4,538
PHARVARIS N V COM
155,105 sh
155,105 sh
NEW
NEW
$3,870
$3,870
DBV TECHNOLOGIES S A SPONSORED ADS
378,594 sh
3,915 sh
1%
1%
$3,786
$354
LEGEND BIOTECH CORP SPONSORED ADS
113,460 sh
-236,540 sh
-68%
-68%
$3,700
-$8,722
ORUKA THERAPEUTICS INC COM
183,330 sh
183,330 sh
NEW
NEW
$3,525
$3,525
UNICYCIVE THERAPEUTICS INC COM NEW
796,558 sh
$3,473
Sana Biotechnology Inc. COM
700,000 sh
700,000 sh
NEW
NEW
$2,485
$2,485
Absci Corp. COM
796,438 sh
796,438 sh
NEW
NEW
$2,421
$2,421
Harmony Biosciences Holdings Inc. COM
Call options for 85,000 sh
85,000 sh
NEW
NEW
$2,343
$2,343
Pliant Therapeutics Inc. COM
850,000 sh
$1,258
CAPRICOR THERAPEUTICS INC COM NEW
Put options for 87,700 sh
87,700 sh
NEW
NEW
$632
$632
AKEBIA THERAPEUTICS INC COM
0 sh
-1,985,915 sh
-100%
-100%
$0
-$7,229
EVOLUS INC COM
0 sh
-720,118 sh
-100%
-100%
$0
-$6,632
KALVISTA PHARMACEUTICALS INC COM
0 sh
-323,170 sh
-100%
-100%
$0
-$3,653
CENTESSA PHARMACEUTICALS PLC SPONSORED ADS
0 sh
-225,000 sh
-100%
-100%
$0
-$2,957
ProMIS Neurosciences Inc COM
0 sh
-2,645,128 sh
-100%
-100%
$0
-$1,280
HELIX ACQUISITION CORP II CL A ORD SHS
0 sh
-29,381 sh
-100%
-100%
$0
-$312