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Great Point Partners LLC 13F filings

Manager(s): Dr. Jeffrey R. Jay, M.D. and Mr. David E. Kroin

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Holdings as of 2020-06-30

Filed on 2020-08-14 under CIK 1281446

Company name, stock class and CUSIPValue (x$1000) SharesOther manager(s)
CONSTELLATION PHARMCETICLS I
COM 210373106
$104,574$42,4213,480,000 sh1,502,498 sh
76%
JAY JEFFREY R
KROIN DAVID
IOVANCE BIOTHERAPEUTICS INC
COM 462260100
$102,251$30,7783,724,976 sh1,337,370 sh
56%
JAY JEFFREY R
KROIN DAVID
ZYMEWORKS INC
COM 98985W102
$92,869$10,4122,574,688 sh250,000 sh
11%
JAY JEFFREY R
KROIN DAVID
ACADIA PHARMACEUTICALS INC
COM 004225108
$87,488$3,1681,804,993 sh-190,754 sh
-10%
JAY JEFFREY R
KROIN DAVID
SAGE THERAPEUTICS INC
COM 78667J108
$87,416$35,0172,102,368 sh277,889 sh
15%
JAY JEFFREY R
KROIN DAVID
ARENA PHARMACEUTICALS INC
COM NEW 040047607
$81,986$65,7111,302,399 sh914,900 sh
236%
JAY JEFFREY R
KROIN DAVID
UNITED THERAPEUTICS CORP DEL
COM 91307C102
$75,020$22,273620,000 sh63,748 sh
11%
JAY JEFFREY R
KROIN DAVID
TG THERAPEUTICS INC
COM 88322Q108
$64,689$54,8493,320,808 sh2,320,808 sh
232%
JAY JEFFREY R
KROIN DAVID
BIOHAVEN PHARMACTL HLDG CO L
COM G11196105
$61,478$27,448840,900 sh-159,100 sh
-16%
JAY JEFFREY R
KROIN DAVID
GW PHARMACEUTICALS PLC
ADS 36197T103
$55,224 450,000 sh JAY JEFFREY R
KROIN DAVID
AKEBIA THERAPEUTICS INC
COM 00972D105
$47,667$47,6673,510,073 sh3,510,073 sh
NEW
JAY JEFFREY R
KROIN DAVID
MACROGENICS INC
COM 556099109
$41,880$41,8801,500,000 sh1,500,000 sh
NEW
JAY JEFFREY R
KROIN DAVID
CYTOKINETICS INC
COM NEW 23282W605
$35,841$28,0111,520,635 sh856,538 sh
129%
JAY JEFFREY R
KROIN DAVID
GLOBAL BLOOD THERAPEUTICS INC
COM 37890U108
$34,229$34,229542,200 sh542,200 sh
NEW
JAY JEFFREY R
KROIN DAVID
GERON CORP
COM 374163103
$33,568$33,56815,398,079 sh15,398,079 sh
NEW
JAY JEFFREY R
KROIN DAVID
Vericel Corp
COM 92346J108
$22,252$22,2521,610,154 sh1,610,154 sh
NEW
JAY JEFFREY R
KROIN DAVID
PROTHENA CORP PLC
SHS G72800108
$21,787 2,082,841 sh JAY JEFFREY R
KROIN DAVID
NEXTCURE INC
COM 65343E108
$21,433-$27,238999,666 sh-313,290 sh
-24%
JAY JEFFREY R
KROIN DAVID
ABEONA THERAPEUTICS INC
COM 00289Y107
$21,026 7,213,012 sh JAY JEFFREY R
KROIN DAVID
GLAUKOS CORP
COM 377322102
$19,210$19,210500,000 sh500,000 sh
NEW
JAY JEFFREY R
KROIN DAVID
MOLECULAR TEMPLATES INC
COM 608550109
$18,553$7,5891,345,397 sh520,397 sh
63%
JAY JEFFREY R
KROIN DAVID
PTC THERAPEUTICS INC
COM 69366J200
$16,744-$61,921330,000 sh-1,433,387 sh
-81%
JAY JEFFREY R
KROIN DAVID
AXONICS MODULATION TECH INC
COM 05465P101
$16,133$2,337459,503 sh-83,426 sh
-15%
JAY JEFFREY R
KROIN DAVID
SANGAMO THERAPEUTICS INC
COM 800677106
$14,156$10,1211,579,891 sh946,386 sh
149%
JAY JEFFREY R
KROIN DAVID
Cytomx Therapeutics Inc
COM 23284F105
$12,067$10,9951,448,604 sh1,308,886 sh
937%
JAY JEFFREY R
KROIN DAVID
CALITHERA BIOSCIENCES INC
COM 13089P101
$11,942$11,9422,261,700 sh2,261,700 sh
NEW
JAY JEFFREY R
KROIN DAVID
LIQUIDIA TECHNOLOGIES INC
COM 53635D202
$10,760 1,277,955 sh JAY JEFFREY R
KROIN DAVID
ARVINAS INC
COM 04335A105
$6,825$2,654Call options for
203,500 sh
100,000 sh
97%
JAY JEFFREY R
KROIN DAVID
Denali Therapeutics
COM 24823R105
$6,770$6,770280,000 sh280,000 sh
NEW
JAY JEFFREY R
KROIN DAVID
VIEWRAY INC
COM 92672L107
$6,213 2,773,811 sh JAY JEFFREY R
KROIN DAVID
OYSTER POINT PHARMA INC
COM 69242L106
$6,199$6,199214,631 sh214,631 sh
NEW
JAY JEFFREY R
KROIN DAVID
Acceleron Pharma Inc
COM 00434H108
$5,531-$42,60658,056 sh-477,571 sh
-89%
JAY JEFFREY R
KROIN DAVID
KADMON HLDGS INC
COM 48283N106
$3,459$3,459675,679 sh675,679 sh
NEW
JAY JEFFREY R
KROIN DAVID
MILLENDO THERAPEUTICS INC
COM 60040X103
$2,571-$6,5621,460,697 sh-269,062 sh
-16%
JAY JEFFREY R
KROIN DAVID
PUMA BIOTECHNOLOGY INC
COM 74587V107
$965$96592,502 sh92,502 sh
NEW
JAY JEFFREY R
KROIN DAVID
NEOLEUKIN THERAPEUTICS INC
COM 64049K104
$233-$22614,065 sh-26,282 sh
-65%
JAY JEFFREY R
KROIN DAVID
ABIOMED INC
COM 003654100
$0-$31,3750 sh-216,144 sh
-100%
JAY JEFFREY R
KROIN DAVID
MOMENTA PHARMACEUTICALS INC
COM 60877T100
$0-$26,6400 sh-979,400 sh
-100%
JAY JEFFREY R
KROIN DAVID
MYOKARDIA INC
COM 62857M105
$0-$23,440Call options for
0 sh
-500,000 sh
-100%
JAY JEFFREY R
KROIN DAVID
CHEMOCENTRYX INC
COM 16383L106
$0-$14,3590 sh-357,379 sh
-100%
JAY JEFFREY R
KROIN DAVID
AXSOME THERAPEUTICS INC
COM 05464T104
$0-$5,8890 sh-100,100 sh
-100%
JAY JEFFREY R
KROIN DAVID
MENLO THERAPEUTICS INC
COM 586858102
$0-$4,4270 sh-1,652,013 sh
-100%
JAY JEFFREY R
KROIN DAVID
KURA ONCOLOGY INC
COM 50127T109
$0-$1,7880 sh-179,700 sh
-100%
JAY JEFFREY R
KROIN DAVID