Great Point Partners 13F filings
Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin
Holdings as of 2025-12-31
Filed on 2026-02-17 under CIK 1281446
Company
Investment Type
Change
Value (x$1000)
increase or decrease
APOGEE THERAPEUTICS INC COM
374,000 sh
70,000 sh
23%
23%
$28,230
$16,152
AMYLYX PHARMACEUTICALS INC COM
1,750,000 sh
50,000 sh
3%
3%
$21,140
-$1,963
ZURA BIO LTD CLASS A ORD SHS
3,815,930 sh
$19,995
DISC MEDICINE INC COM
250,000 sh
250,000 sh
NEW
NEW
$19,853
$19,853
RAPT THERAPEUTICS INC COM
581,187 sh
581,187 sh
NEW
NEW
$19,685
$19,685
IMMUNOVANT INC COM
750,000 sh
250,000 sh
50%
50%
$19,065
$11,005
SOLENO THERAPEUTICS INC COM
400,000 sh
175,000 sh
78%
78%
$18,520
$3,310
VOR BIOPHARMA INC COM NEW
1,370,107 sh
1,370,107 sh
NEW
NEW
$17,921
$17,921
DIANTHUS THERAPEUTICS INC COM
350,000 sh
84,197 sh
32%
32%
$14,424
$3,965
JADE BIOSCIENCES INC COM NEW
806,273 sh
173,674 sh
27%
27%
$12,441
$6,982
KALVISTA PHARMACEUTICALS INC COM
685,632 sh
685,632 sh
NEW
NEW
$11,073
$11,073
CONTINEUM THERAPEUTICS INC CL A
800,000 sh
800,000 sh
NEW
NEW
$9,144
$9,144
EUPRAXIA PHARMACEUTICALS INC COM
1,200,000 sh
$9,060
NEKTAR THERAPEUTICS COM NEW
210,732 sh
-89,268 sh
-30%
-30%
$8,910
-$8,160
UPSTREAM BIO INC COM
300,000 sh
$8,145
NEUROGENE INC COM
350,000 sh
-96,814 sh
-22%
-22%
$7,210
-$533
CONTEXT THERAPEUTICS INC COM COM
4,683,711 sh
$6,885
EVOMMUNE ORD COM SHS
325,000 sh
325,000 sh
NEW
NEW
$5,564
$5,564
ORUKA THERAPEUTICS INC COM
183,330 sh
$5,557
SILENCE THERAPEUTICS PLC ADS
808,032 sh
808,032 sh
NEW
NEW
$4,913
$4,913
UNICYCIVE THERAPEUTICS INC COM NEW
796,558 sh
$4,596
Eliem Therapeutics Inc. COM
979,534 sh
979,534 sh
NEW
NEW
$3,918
$3,918
Sana Biotechnology Inc. COM
700,000 sh
$2,849
PHARVARIS N V COM
82,800 sh
-72,305 sh
-47%
-47%
$2,298
-$1,572
AVALO THERAPEUTICS ORD COM
124,666 sh
124,666 sh
NEW
NEW
$2,264
$2,264
Rezolute Inc. COM NEW
951,809 sh
-1,500,000 sh
-61%
-61%
$2,246
-$20,801
ASCENDIS PHARMA A S SPONSORED ADR
0 sh
-75,000 sh
-100%
-100%
$0
-$14,911
Abivax SA F Sponsored ADR Stock
0 sh
-150,000 sh
-100%
-100%
$0
-$12,735
CYTOKINETICS INC COM NEW
0 sh
-150,000 sh
-100%
-100%
$0
-$8,244
XENON PHARMACEUTICALS INC COM
0 sh
-200,000 sh
-100%
-100%
$0
-$8,030
AKERO THERAPEUTICS INC COM
0 sh
-103,848 sh
-100%
-100%
$0
-$4,931
Taysha Gene Therapies Inc. COM
0 sh
-1,500,000 sh
-100%
-100%
$0
-$4,905
DBV TECHNOLOGIES S A SPONSORED ADS
0 sh
-378,594 sh
-100%
-100%
$0
-$3,786
LEGEND BIOTECH CORP SPONSORED ADS
0 sh
-113,460 sh
-100%
-100%
$0
-$3,700
Absci Corp. COM
0 sh
-796,438 sh
-100%
-100%
$0
-$2,421
Harmony Biosciences Holdings Inc. COM
Call options for 0 sh
-85,000 sh
-100%
-100%
$0
-$2,343
Pliant Therapeutics Inc. COM
0 sh
-850,000 sh
-100%
-100%
$0
-$1,258
CAPRICOR THERAPEUTICS INC COM NEW
Put options for 0 sh
-87,700 sh
-100%
-100%
$0
-$632