Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin
Company
Investment Type
Change
Value (x$1000)
increase or decrease
XENON PHARMACEUTICALS INC COM
1,104,334 sh
184,334 sh
20%
$33,594
$5,470
190,000 sh
35,000 sh
23%
$29,642
$5,513
CYTOKINETICS INC COM NEW
610,000 sh
-40,000 sh
-6%
$23,967
$40
971,233 sh
-38,767 sh
-4%
$23,533
-$2,495
Put options for 150,000 sh
150,000 sh
NEW
$21,878
$21,878
VAXCYTE INC COM
985,153 sh
100,000 sh
11%
$21,437
$61
GALAPAGOS NV SPON ADR
360,000 sh
$20,088
KARUNA THERAPEUTICS INC COM
149,000 sh
149,000 sh
NEW
$18,850
$18,850
POINT BIOPHARMA GLOBAL INC COM
2,420,501 sh
360,501 sh
18%
$16,484
$66
ACLARIS THERAPEUTICS INC COM
1,083,000 sh
140,555 sh
15%
$15,119
-$1,129
KALVISTA PHARMACEUTICALS INC COM
1,530,000 sh
655,803 sh
75%
$15,055
$2,169
193,900 sh
193,900 sh
NEW
$14,535
$14,535
RELMADA THERAPEUTICS INC COM
700,000 sh
-90,000 sh
-11%
$13,293
-$8,029
CINCOR PHARMA INC COM
669,200 sh
589,530 sh
740%
$12,608
$11,211
3,150,000 sh
3,050,000 sh
3050%
$11,970
$11,431
KINIKSA PHARMACEUTICALS LTD COM CL A
1,204,028 sh
85,961 sh
8%
$11,667
$553
TRICIDA INC COM
1,164,763 sh
-85,237 sh
-7%
$11,275
$1,000
361,636 sh
361,636 sh
NEW
$10,773
$10,773
5,755,396 sh
5,755,396 sh
NEW
$9,209
$9,209
453,118 sh
-246,882 sh
-35%
$9,198
-$8,120
75,000 sh
75,000 sh
NEW
$7,311
$7,311
UROGEN PHARMA LTD COM
873,424 sh
$7,153
ACUMEN PHARMACEUTICALS INC COM
1,515,000 sh
586,718 sh
63%
$7,121
$3,491
KARUNA THERAPEUTICS INC COM
Put options for 54,900 sh
54,900 sh
NEW
$6,945
$6,945
Chinook Therapeutics
336,731 sh
-1,086,951 sh
-76%
$5,889
-$17,402
VENTYX BIOSCIENCES INC COM
389,223 sh
52,889 sh
16%
$4,760
$196
SILENCE THERAPEUTICS PLC ADS
401,449 sh
-42,994 sh
-10%
$4,757
-$3,687
2,512,500 sh
313,424 sh
14%
$4,698
-$1,965
ALPINE IMMUNE SCIENCES INC COM
538,819 sh
538,819 sh
NEW
$4,585
$4,585
89BIO INC COM
1,400,000 sh
1,400,000 sh
NEW
$4,508
$4,508
PLIANT THERAPEUTICS, INC. COM
357,263 sh
357,263 sh
NEW
$2,862
$2,862
MOONLAKE IMMUNOT COMMON STOCK
432,000 sh
432,000 sh
NEW
$2,268
$2,268
Magenta Therapeutics Inc COM
1,170,000 sh
$1,404
AEGLEA BIOTHERAPEUTICS INC COM
2,500,000 sh
2,500,000 sh
NEW
$1,263
$1,263
0 sh
-1,300,000 sh
-100%
$0
-$29,471
BICYCLE THERAPEUTICS PLC SPONSORED ADS
0 sh
-550,592 sh
-100%
$0
-$24,160
0 sh
-85,000 sh
-100%
$0
-$22,182
0 sh
-4,000,000 sh
-100%
$0
-$11,960
ARDELYX INC COM
0 sh
-4,761,905 sh
-100%
$0
-$5,095
PASSAGE BIO, INC. Common Stock, par value $0.0001 per share
0 sh
-113,900 sh
-100%
$0
-$353
0 sh
-121,000 sh
-100%
$0
-$304