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Great Point Partners LLC 13F filings

Manager(s): Dr. Jeffrey Jay, M.D. and Mr. David Kroin

Holdings as of 2022-03-31

Filed on 2022-05-16 under CIK 1281446

Company
Investment Type
Change
Value (x$1000)
increase or decrease
EXELIXIS INC
1,300,000 sh
-450,000 sh
-26%
$29,471
-$2,519
XENON PHARMACEUTICALS INC COM
920,000 sh
-30,000 sh
-3%
$28,124
-$1,554
TRAVERE THERAPEUTICS INC
1,010,000 sh
210,000 sh
26%
$26,028
$1,196
BICYCLE THERAPEUTICS PLC SPONSORED ADS
550,592 sh
350,592 sh
175%
$24,160
$11,986
JAZZ PHARMACEUTICALS PLC
155,000 sh
155,000 sh
NEW
$24,129
$24,129
CYTOKINETICS INC COM NEW
650,000 sh
300,000 sh
86%
$23,927
$7,974
Chinook Therapeutics
1,423,682 sh
1,033,641 sh
265%
$23,291
$16,929
GALAPAGOS NV SPON ADR
360,000 sh
60,000 sh
20%
$22,327
$5,788
VERTEX PHARMACEUTICALS INC
85,000 sh
 
$22,182
VAXCYTE INC COM
885,153 sh
385,153 sh
77%
$21,376
$9,481
RELMADA THERAPEUTICS INC COM
790,000 sh
72,680 sh
10%
$21,322
$5,161
ANAPTYSBIO INC
700,000 sh
107,750 sh
18%
$17,318
-$3,263
POINT BIOPHARMA GLOBAL INC COM
2,060,000 sh
1,869,480 sh
981%
$16,418
$15,351
ACLARIS THERAPEUTICS INC COM
942,445 sh
142,445 sh
18%
$16,248
$4,616
KALVISTA PHARMACEUTICALS INC COM
874,197 sh
462,260 sh
112%
$12,886
$7,436
RIGEL PHARMACEUTICALS INC
4,000,000 sh
-1,000,000 sh
-20%
$11,960
-$1,290
KINIKSA PHARMACEUTICALS LTD COM CL A
1,118,067 sh
581,329 sh
108%
$11,114
$4,797
TRICIDA INC COM
1,250,000 sh
-150,000 sh
-11%
$10,275
-$3,109
AVIDITY BIOSCIENCES INC
500,000 sh
 
$9,235
SILENCE THERAPEUTICS PLC ADS
444,443 sh
 
$8,444
UROGEN PHARMA LTD COM
873,424 sh
 
$7,608
PIERIS PHARMACEUTICALS INC
2,199,076 sh
649,076 sh
42%
$6,663
$804
ARDELYX INC COM
4,761,905 sh
4,761,905 sh
NEW
$5,095
$5,095
VENTYX BIOSCIENCES INC COM
336,334 sh
336,334 sh
NEW
$4,564
$4,564
ACUMEN PHARMACEUTICALS INC COM
928,282 sh
928,282 sh
NEW
$3,630
$3,630
Magenta Therapeutics Inc COM
1,170,000 sh
 
$3,393
CINCOR PHARMA INC COM
79,670 sh
79,670 sh
NEW
$1,397
$1,397
NEKTAR THERAPEUTICS

Call options for 100,000 sh
-103,900 sh
-51%
$539
-$2,216
PASSAGE BIO, INC. Common Stock, par value $0.0001 per share
113,900 sh
-1,404,195 sh
-92%
$353
-$9,287
RAFAEL HLDGS INC
121,000 sh
-164,714 sh
-58%
$304
-$1,153
ARENA PHARMACEUTICALS INC COM NEW
0 sh
-530,670 sh
-100%
$0
-$49,320
BIOATLA INC COM
0 sh
-864,300 sh
-100%
$0
-$16,966
MACROGENICS INC
0 sh
-1,000,000 sh
-100%
$0
-$16,050
SAREPTA THERAPEUTICS INC
0 sh
-145,405 sh
-100%
$0
-$13,094
ROCKET PHARMACEUTICALS INC COM
0 sh
-500,526 sh
-100%
$0
-$10,926
DYNE THERAPEUTICS INC COM
0 sh
-845,000 sh
-100%
$0
-$10,047
PROQR THRAPEUTICS N V SHS EURO
0 sh
-1,121,122 sh
-100%
$0
-$8,980
PYXIS ONCOLOGY INC COM
0 sh
-400,000 sh
-100%
$0
-$4,388
AEGLEA BIOTHERAPEUTICS INC COM
0 sh
-910,251 sh
-100%
$0
-$4,324
ARBUTUS BIOPHARMA CORP COM
0 sh
-668,907 sh
-100%
$0
-$2,602
CABALETTA BIO INC COM
0 sh
-472,433 sh
-100%
$0
-$1,791